Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria

Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria

Recent years have seen an unprecedented rise in the incidence of multidrug-resistant (MDR) Gram-negative bacteria (GNBs) such as Acinetobacter and Klebsiella species. In view of the shortage of novel drugs in the pipeline, alternative strategies to prevent, and treat infections by GNBs are urgently...

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Bibliographic Details
Main Authors: Eman G. Youssef, Lina Zhang, Sondus Alkhazraji, Teclegiorgis Gebremariam, Shakti Singh, Nannette Y. Yount, Michael R. Yeaman, Priya Uppuluri, Ashraf S. Ibrahim
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
monoclonal antibodies
Candida Hyr1
Acinetobacter baumannii
Klebsiella pneumoniae
passive vaccine
molecular modeling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00076/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00076/full

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