Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients

Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients

<p>Abstract</p> <p>Our hypothesis was that overexpression of certain lipoprotein receptors might be related to lipid accumulation in the human ischemic myocardium. Intramyocardial lipid overload contributes to contractile dysfunction and arrhythmias in cardiomyopathy. Thus, the pur...

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Bibliographic Details
Main Authors: Cal Roi, Juan-Babot Oriol, Brossa Vicenç, Roura Santiago, Gálvez-Montón Carolina, Portoles Manolo, Rivera Miguel, Cinca Juan, Badimon Lina, Llorente-Cortés Vicenta
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Translational Medicine
Subjects:
Ischemic cardiomyopathy
LRP1
VLDLR
HIF-1α myocardial lipid accumulation
Online Access:http://www.translational-medicine.com/content/10/1/160

Internet

http://www.translational-medicine.com/content/10/1/160

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