Genome-Scale Metabolic Reconstruction and <i>in Silico</i> Perturbation Analysis of the Polar Diatom <i>Fragilariopsis cylindrus</i> Predicts High Metabolic Robustness

Genome-Scale Metabolic Reconstruction and <i>in Silico</i> Perturbation Analysis of the Polar Diatom <i>Fragilariopsis cylindrus</i> Predicts High Metabolic Robustness

Diatoms are major primary producers in polar environments where they can actively grow under extremely variable conditions. Integrative modeling using a genome-scale model (GSM) is a powerful approach to decipher the complex interactions between components of diatom metabolism and can provide insigh...

Full description

Bibliographic Details
Main Authors: Michel Lavoie, Blanche Saint-Béat, Jan Strauss, Sébastien Guérin, Antoine Allard, Simon V. Hardy, Angela Falciatore, Johann Lavaud
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biology
Subjects:
flux balance analysis
metabolic network
arctic
systems biology
reaction deletion
gene deletion
Online Access:https://www.mdpi.com/2079-7737/9/2/30

Internet

https://www.mdpi.com/2079-7737/9/2/30

Similar Items