CSB affected on the sensitivity of lung cancer cells to platinum-based drugs through the global decrease of let-7 and miR-29

CSB affected on the sensitivity of lung cancer cells to platinum-based drugs through the global decrease of let-7 and miR-29

Abstract Background Transcription-coupled nucleotide excision repair (TC-NER) plays a prominent role in the removal of DNA adducts induced by platinum-based chemotherapy reagents. Cockayne syndrome protein B (CSB), the master sensor of TCR, is also involved in the platinum resistant. Let-7 and miR-2...

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Bibliographic Details
Main Authors: Zhenbang Yang, Chunling Liu, Hongjiao Wu, Yuning Xie, Hui Gao, Xuemei Zhang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
CSB
Let-7
miR-29
Platinum
Lung cancer
Online Access:http://link.springer.com/article/10.1186/s12885-019-6194-z

Internet

http://link.springer.com/article/10.1186/s12885-019-6194-z

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