Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro

Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro

Abstract Background Equine malignant melanoma (EMM) is a frequently occurring dermoepidermal tumor in grey horses. Currently available therapies are either challenging or inefficient. Betulinic acid (BA), a naturally occurring triterpenoid, is a promising compound for cancer treatment. To evaluate t...

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Bibliographic Details
Main Authors: Lisa A. Weber, Jessica Meißner, Julien Delarocque, Jutta Kalbitz, Karsten Feige, Manfred Kietzmann, Anne Michaelis, Reinhard Paschke, Julia Michael, Barbara Pratscher, Jessika-M. V. Cavalleri
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Veterinary Research
Subjects:
Equine malignant melanoma (EMM)
Betulinic acid
Cell culture assay
Franz-type diffusion cell
Online Access:https://doi.org/10.1186/s12917-020-2262-5

Internet

https://doi.org/10.1186/s12917-020-2262-5

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