CXCR4 expression in lung carcinogenesis: Evaluating gender-specific differences in survival outcomes based on CXCR4 expression in early stage non-small cell lung cancer patients.

<h4>Introduction</h4>Evidence suggests that the expression of certain cytokine receptors increases with lung cancer evolution. Overexpression of the cytokine receptor CXCR4 is associated with poor outcomes in stage IV non-small cell lung cancer (NSCLC), with shorter survival in females w...

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Bibliographic Details
Main Authors: Andrea S Fung, Karen Kopciuk, Michelle L Dean, Adrijana D'Silva, Shannon Otsuka, Alexander Klimowicz, Desiree Hao, Don Morris, D Gwyn Bebb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241240