Deciphering the Association of Cytokines, Chemokines, and Growth Factors in Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Using an ex vivo Osteochondral Culture System

Deciphering the Association of Cytokines, Chemokines, and Growth Factors in Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Using an ex vivo Osteochondral Culture System

Osteoarthritis (OA) is a chronic degenerative joint disorder associated with degradation and decreased production of the extracellular matrix, eventually leading to cartilage destruction. Limited chondrocyte turnover, structural damage, and prevailing inflammatory milieu prevent efficient cartilage...

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Bibliographic Details
Main Authors: Mohammad Alam Jafri, Gauthaman Kalamegam, Mohammed Abbas, Mohammed Al-Kaff, Farid Ahmed, Sherin Bakhashab, Mahmood Rasool, Muhammad Imran Naseer, Vasan Sinnadurai, Peter Natesan Pushparaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoarthritis
stem cells
cartilage
xMAP technology
cytokines
chemokines
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00380/full

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https://www.frontiersin.org/article/10.3389/fcell.2019.00380/full

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