Targeting Caspase 8: Using Structural and Ligand-Based Approaches to Identify Potential Leads for the Treatment of Multi-Neurodegenerative Diseases

Caspase 8 is a central player in the apoptotic cell death pathway and is also essential for cytokine processing. The critical role of this protease in cell death pathways has generated research interest because its activation has also been linked with neural cell death. Thus, blocking the activity o...

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Bibliographic Details
Main Authors: Khurshid Ahmad, Vishal M. Balaramnavar, Navaneet Chaturvedi, Saif Khan, Shafiul Haque, Yong-Ho Lee, Inho Choi
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/9/1827