ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids
Objective: Enteroendocrine cells (EECs) survey the gut luminal environment and coordinate hormonal, immune and neuronal responses to it. They exhibit well-characterised physiological roles ranging from the control of local gut function to whole body metabolism, but little is known regarding the regu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-04-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221287782030020X |