Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve.

There are great opportunities in the manipulation of bacterial mechanosensitive (MS) ion channels for specific and targeted drug delivery purposes. Recent research has shown that these ion channels have the potential to be converted into nanovalves through clever use of magnetic nanoparticles and ma...

Full description

Bibliographic Details
Main Authors: Adam D Martinac, Navid Bavi, Omid Bavi, Boris Martinac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5578686?pdf=render