Neuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats

Despite the efficacy of combination antiretroviral therapy (ART) in controlling human immunodeficiency virus (HIV-1) replication, cytotoxic viral proteins such as HIV-1 transactivator of transcription (Tat) persist in tissues such as the brain. Although HIV-1 does not infect neuronal cells, it is su...

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Bibliographic Details
Main Authors: Raghubendra Singh Dagur, Ke Liao, Susmita Sil, Fang Niu, Zhiqiang Sun, Yuri L. Lyubchenko, Eric S. Peeples, Guoku Hu, Shilpa Buch
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://dx.doi.org/10.1080/20013078.2019.1703249