HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol.

<h4>Background</h4>Some mutations in the HIV-1 Gag gene are known to confer resistance to ritonavir-boosted protease inhibitors (PI/r), but their clinical implications remain controversial. This review aims at summarizing current knowledge on HIV-1 Gag gene mutations that are selected un...

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Main Authors: Alex Durand Nka, Georges Teto, Maria Mercedes Santoro, Valantine Ngum Ndze, Désiré Takou, Beatrice Dambaya, Ezechiel Ngoufack Jagni Semengue, Lavinia Fabeni, Carlo-Federico Perno, Vittorio Colizzi, Francesca Ceccherini-Silberstein, Joseph Fokam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253587