The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

Abstract Background Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from the Chinese medicinal herb Stephania tetrandra S. Moore. We previously demonstrated that tetrandrine exhibits potent antitumor effects in many types of cancer cells. In this study, we investigated the effects of tetran...

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Bibliographic Details
Main Authors: Zhenxing Zhang, Ting Liu, Man Yu, Kangdi Li, Wenhua Li
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Autophagy
Metastasis
MTA1
Tetrandrine
Wnt/β-catenin
Epithelial-Mesenchymal transition (EMT)
Online Access:http://link.springer.com/article/10.1186/s13046-018-0678-6

Internet

http://link.springer.com/article/10.1186/s13046-018-0678-6

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