De novo Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application

De novo Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application

Neurodevelopmental and psychiatric disorders are a highly disabling and heterogeneous group of developmental and mental disorders, resulting from complex interactions of genetic and environmental risk factors. The nature of multifactorial traits and the presence of comorbidity and polygenicity in th...

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Bibliographic Details
Main Authors: Weidi Wang, Roser Corominas, Guan Ning Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
whole exome sequencing
neurodevelopmental and psychiatric disorder
de novo mutation
network analysis
clinical implementation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00258/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00258/full

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