Evaluating the effect of therapeutic stem cells on TRAIL resistant and sensitive medulloblastomas.

Mesenchymal stem cells (MSC) are emerging as novel cell-based delivery agents; however, a thorough investigation addressing their therapeutic potential in medulloblastomas (MB) has not been explored to date. In this study, we engineered human MSC to express a potent and secretable variant of a tumor...

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Bibliographic Details
Main Authors: Irina Nesterenko, Simone Wanningen, Tugba Bagci-Onder, Maarten Anderegg, Khalid Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492275?pdf=render