circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity

circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity

Circular RNAs (circRNA) is a class of non-coding RNAs that can regulate gene translation and function. Here the authors show that a circRNA, circNDUFB2, is downregulated in non-small cell lung cancer tissues, and likely contributes to anti-tumor immunity by regulating both degradation of oncoprotein...

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Bibliographic Details
Main Authors: Botai Li, Lili Zhu, Chunlai Lu, Cun Wang, Hui Wang, Haojie Jin, Xuhui Ma, Zhuoan Cheng, Chengtao Yu, Siying Wang, Qiaozhu Zuo, Yangyang Zhou, Jun Wang, Chen Yang, Yuanyuan Lv, Liyan Jiang, Wenxin Qin
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20527-z

Internet

https://doi.org/10.1038/s41467-020-20527-z

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