Co-Immunization With CHIKV VLP and DNA Vaccines Induces a Promising Humoral Response in Mice

Chikungunya fever is an acute infectious disease that is mediated by the mosquito-transmitted chikungunya virus (CHIKV), for which no licensed vaccines are currently available. Here, we explored several immunization protocols and investigated their immunity and protective effects in mice, with DNA-...

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Bibliographic Details
Main Authors: Zhimin Zhao, Yao Deng, Peihua Niu, Jingdong Song, Wen Wang, Yongping Du, Baoying Huang, Wenling Wang, Leiliang Zhang, Ping Zhao, Wenjie Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.655743/full