Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity

Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity

Abstract Objective The Hairy Enhancer of Split 1 (HES1) is a transcriptional repressor that regulates cellular proliferation and differentiation during development. We previously found an interaction between HES1 and Fanconi anemia (FA) proteins. FA is a hematological and developmental disorder caus...

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Bibliographic Details
Main Authors: Cédric S. Tremblay, Feng Fei Huang, Georges Lévesque, Madeleine Carreau
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Research Notes
Subjects:
Hairy-Enhancer of Split-1
HES1
Fanconi anemia
Ubiquitination
Mono-ubiquitination
Online Access:http://link.springer.com/article/10.1186/s13104-018-3243-7

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http://link.springer.com/article/10.1186/s13104-018-3243-7

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