Mining Small Routine Clinical Data: A Population Pharmacokinetic Model and Optimal Sampling Times of Capecitabine and its Metabolites

Purpose: The present study was performed to demonstrate that small amounts of routine clinical data allow to generate valuable knowledge. Concretely, the aims of this research were to build a joint population pharmacokinetic model for capecitabine and three of its metabolites (5-DFUR, 5-FU and 5-FU...

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Bibliographic Details
Main Authors: Esther Oyaga-Iriarte, Asier Insausti, Lorea Bueno, Onintza Sayar, Azucena Aldaz
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2019-04-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/30392