Avidin-biotin technology to synthesize multi-arm nano-construct for drug delivery

Here we describe methods for synthesizing a cationic, multi-arm Avidin (mAv) nano-construct that has a wide range of applications in drug delivery and imaging of negatively charged tissues. We use Avidin-biotin technology that gives the flexibility for conjugating biotinylated Dexamethasone to mAv b...

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Bibliographic Details
Main Authors: Chenzhen Zhang, Tengfei He, Armin Vedadghavami, Ambika G. Bajpayee
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016120301011