Enzymatic and transcriptional regulation of the cytoplasmic acetyl-CoA hydrolase ACOT12

Enzymatic and transcriptional regulation of the cytoplasmic acetyl-CoA hydrolase ACOT12

Acyl-CoA thioesterase 12 (ACOT12) is the major enzyme known to hydrolyze the thioester bond of acetyl-CoA in the cytosol in the liver. ACOT12 contains a catalytic thioesterase domain at the N terminus and a steroidogenic acute regulatory protein-related lipid transfer (START) domain at the C terminu...

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Bibliographic Details
Main Authors: Yasuhiro Horibata, Hiromi Ando, Masahiko Itoh, Hiroyuki Sugimoto
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Journal of Lipid Research
Subjects:
acyl-CoA thioesterase 12
phosphatidic acid
steroidogenic acute regulatory protein-related lipid transfer domain protein
lipid biosynthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520375222

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http://www.sciencedirect.com/science/article/pii/S0022227520375222

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