Regulation of Renin Release via Cyclic ADP-Ribose-Mediated Signaling: Evidence from Mice Lacking CD38 Gene

Regulation of Renin Release via Cyclic ADP-Ribose-Mediated Signaling: Evidence from Mice Lacking CD38 Gene

Background/Aims: Despite extensive studies, the intracellular regulatory mechanism of renin production and release is still poorly understood. The present study was designed to test whether CD38-ADP-ribosylcyclase signaling pathway contributes to the regulation of renin production and release, and t...

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Bibliographic Details
Main Authors: Jing Xiong, Min Xia, Fan Yi, Justine M. Abais, Ningjun Li, Krishna M. Boini, Pin-Lan Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
ADP-ribosylcyclase
Ca2+ signaling
Renin angiotensin II system
Renal hemodynamics
Juxtaglomerular apparatus
Online Access:http://www.karger.com/Article/FullText/343348

Internet

http://www.karger.com/Article/FullText/343348

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