Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development

Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development

To spatially co-exist and differentially specify fates within developing tissues, morphogenetic cues must be correctly positioned and interpreted. Here, we investigate mouse hair follicle development to understand how morphogens operate within closely spaced, fate-diverging progenitors. Coupling tra...

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Bibliographic Details
Main Authors: Irina Matos, Amma Asare, John Levorse, Tamara Ouspenskaia, June de la Cruz-Racelis, Laura-Nadine Schuhmacher, Elaine Fuchs
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
morphogenesis
morphogen gradient
positional information
pattern formation
stem cells
sharp boundary formation
Online Access:https://elifesciences.org/articles/54304

Internet

https://elifesciences.org/articles/54304

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