Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments

Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments

Evolve-and-resequence (E+R) experiments leverage next-generation sequencing technology to track the allele frequency dynamics of populations as they evolve. While previous work has shown that adaptive alleles can be detected by comparing frequency trajectories from many replicate populations, this p...

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Bibliographic Details
Main Authors: Susanne Tilk, Alan Bergland, Aaron Goodman, Paul Schmidt, Dmitri Petrov, Sharon Greenblum
Format: Article
Language:English
Published: Oxford University Press 2019-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
evolve-and-resequence
allele frequencies
coverage
adaptation
haplotypes
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400755

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400755

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