Study of CD27 and CCR4 Markers on Specific CD4+ T-Cells as Immune Tools for Active and Latent Tuberculosis Management

The immunological characterization of different cell markers has opened the possibility of considering them as immune tools for tuberculosis (TB) management, as they could correlate with TB latency/disease status and outcome. CD4+ T-cells producing IFN-γ+ with a low expression of CD27 have been desc...

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Main Authors: Irene Latorre, Marco A. Fernández-Sanmartín, Beatriz Muriel-Moreno, Raquel Villar-Hernández, Sergi Vila, Maria L. De Souza-Galvão, Zoran Stojanovic, María Á. Jiménez-Fuentes, Carmen Centeno, Juan Ruiz-Manzano, Joan-Pau Millet, Israel Molina-Pinargote, Yoel D. González-Díaz, Alicia Lacoma, Lydia Luque-Chacón, Josefina Sabriá, Cristina Prat, Jose Domínguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03094/full