Thematic review series: Lipid Posttranslational Modifications CAAX modification and membrane targeting of Ras
Proteins that terminate with a consensus sequence known as CAAX undergo a series of posttranslational modifications that include polyisoprenylation, endoproteolysis, and carboxyl methylation. These modifications render otherwise hydrophilic proteins hydrophobic at their C termini such that they asso...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520332363 |