Machine learning with random subspace ensembles identifies antimicrobial resistance determinants from pan-genomes of three pathogens.

The evolution of antimicrobial resistance (AMR) poses a persistent threat to global public health. Sequencing efforts have already yielded genome sequences for thousands of resistant microbial isolates and require robust computational tools to systematically elucidate the genetic basis for AMR. Here...

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Bibliographic Details
Main Authors: Jason C Hyun, Erol S Kavvas, Jonathan M Monk, Bernhard O Palsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007608