Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans

Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans

We aimed at establishing a sensitive and robust assay for estimation of systemic complement activation at complement component C3 level in mouse and human plasma samples. In order to capture the activation products iC3b and C3dg in a specific and physiological relevant manner we utilized a construct...

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Bibliographic Details
Main Authors: Lene Halkjær, Anne Troldborg, Henrik Pedersen, Lisbeth Jensen, Annette Gudmann Hansen, Troels Krarup Hansen, Mette Bjerre, Jakob Appel Østergaard, Steffen Thiel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
complement activation
complement receptor 2
immunoassay
C3dg
iC3b
mouse
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00774/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00774/full

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