Degradation Products of Tryptophan in Cell Culture Media: Contribution to Color and Toxicity

Degradation Products of Tryptophan in Cell Culture Media: Contribution to Color and Toxicity

Biomanufacturing processes may be optimized by storing cell culture media at room temperature, but this is currently limited by their instability and change in color upon long-term storage. This study demonstrates that one of the critical contributing factors toward media browning is tryptophan. LC-...

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Bibliographic Details
Main Authors: Alisa Schnellbaecher, Anton Lindig, Maxime Le Mignon, Tim Hofmann, Brit Pardon, Stephanie Bellmaine, Aline Zimmer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
tryptophan
color
cell culture media
LC-MS
antioxidant
cytotoxicity
Online Access:https://www.mdpi.com/1422-0067/22/12/6221

Internet

https://www.mdpi.com/1422-0067/22/12/6221

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