E3 Ubiquitin Ligase-Mediated Regulation of Osteoblast Differentiation and Bone Formation

E3 Ubiquitin Ligase-Mediated Regulation of Osteoblast Differentiation and Bone Formation

The ubiquitin–proteasome system (UPS) is an essential pathway that regulates the homeostasis and function of intracellular proteins and is a crucial protein-degradation system in osteoblast differentiation and bone formation. Abnormal regulation of ubiquitination leads to osteoblast differentiation...

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Bibliographic Details
Main Authors: Jianlin Shen, Bowen Fu, Yanfang Li, Yanjiao Wu, Hongxun Sang, Heshi Zhang, Haibin Lin, Huan Liu, Wenhua Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
E3 ubiquitin ligase
transcription factor
signaling pathway
osteoblast differentiation
bone formation
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.706395/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.706395/full

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