Development of a High-throughput Agar Colony Formation Assay to Identify Drug Candidates against Medulloblastoma

Medulloblastoma (MB) is the most common malignant childhood brain cancer. High-risk MB tumours have a high incidence of metastasis and result in poor patient survival. Drug screens, commonly used to identify potential novel therapeutic agents against MB, focus on 2D cell proliferation and viability...

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Bibliographic Details
Main Authors: Mohammed Sedeeq, Ahmed Maklad, Nuri Gueven, Iman Azimi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/11/368