Methyl 4-Hydroxy-2,2-Dioxo-1<i>H</i>-2λ<sup>6</sup>,1-Benzothiazine-3-Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics

Methyl 4-Hydroxy-2,2-Dioxo-1<i>H</i>-2λ<sup>6</sup>,1-Benzothiazine-3-Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics

In order to identify new regularities of the &#8220;structure&#8722;analgesic activity&#8221; relationship in the series of 2,1-benzothiazine derivatives, the synthesis of methyl 4-hydroxy-2,2-dioxo-1<i>H</i>-2&#955;<sup>6</sup>,1-benzothiazine-3-carboxylate a...

Full description

Bibliographic Details
Main Authors: Igor V. Ukrainets, Lidiya A. Petrushova, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Tatiana V. Alekseeva, Inna I. Torianyk, Alexandra A. Davidenko
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2020-03-01
Series:Scientia Pharmaceutica
Subjects:
2,1-benzothiazine
esters
4-hydroxy-2,2-dioxo-1<i>h</i>-2λ<sup>6</sup>,1-benzothiazine-3-carboxylic acid
crystal structure
molecular conformation
analgesic activity
Online Access:https://www.mdpi.com/2218-0532/88/1/10

Internet

https://www.mdpi.com/2218-0532/88/1/10

Similar Items