Growth factor-mediated augmentation of long bones: evaluation of a BMP-7 loaded thermoresponsive hydrogel in a murine femoral intramedullary injection model

Growth factor-mediated augmentation of long bones: evaluation of a BMP-7 loaded thermoresponsive hydrogel in a murine femoral intramedullary injection model

Abstract Background Due to our aging population, an increase in proximal femur fractures can be expected, which is associated with impaired activities of daily living and a high risk of mortality. These patients are also at a high risk to suffer a secondary osteoporosis-related fracture on the contr...

Full description

Bibliographic Details
Main Authors: Carl Neuerburg, Lena M. Mittlmeier, Alexander M. Keppler, Ines Westphal, Änne Glass, Maximilian M. Saller, Philipp K. E. Herlyn, Heiko Richter, Wolfgang Böcker, Matthias Schieker, Attila Aszodi, Dagmar-C. Fischer
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoporosis
Murine femoral intramedullary injection model
Bone morphogenetic protein 7 (BMP-7)
BDI-hydrogel
Online Access:http://link.springer.com/article/10.1186/s13018-019-1315-6

Internet

http://link.springer.com/article/10.1186/s13018-019-1315-6

Similar Items