TRIM5α selectively binds a restriction-sensitive retroviral capsid
<p>Abstract</p> <p>TRIM5 is a potent retrovirus inhibitor that targets viruses bearing particular capsid (CA) residues. In most primate species, retroviral restriction requires the C-terminal SPRY domain unique to the α-isoform of TRIM5, but the mechanism by which susceptible virus...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-06-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/2/1/40 |