An efficient de novo synthesis of 3'-deoxythymidine from D-xylose

An efficient de novo synthesis of 3'-deoxythymidine from D-xylose

An efficient stereospecific synthesis of 3’-deoxythymidine has been achieved, starting from D-xylose. The key step of the synthesis involved the NBS promoted conversion of 5-O-benzoyl-2,3-di-S-ethyl-2,3-dithio-D-ribose diethyl dithioacetal (4) into the 1-O-acetyl-5-O-benzoyl-2,3-di-S-ethyl-2,3-dithi...

Full description

Bibliographic Details
Main Authors: Ćetković Gordana S., Lajšić Stevan, Popsavin Mirjana M., Popsavin Velimir J., Miljković Dušan
Format: Article
Language:English
Published: Serbian Chemical Society 2002-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
3'-deoxythymidine
dethioacetalization
n-glycosylation
modified nucleosides
d-xylose.
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390201001C.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390201001C.pdf

Similar Items