The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.

BACKGROUND: Chronic hepatitis C (CH) can develop into liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully...

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Main Authors: Yoshiki Murakami, Hidenori Toyoda, Masami Tanaka, Masahiko Kuroda, Yoshinori Harada, Fumihiko Matsuda, Atsushi Tajima, Nobuyoshi Kosaka, Takahiro Ochiya, Kunitada Shimotohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025920?pdf=render