A therapeutic vascular conduit to support in vivo cell-secreted therapy

Abstract A significant barrier to implementation of cell-based therapies is providing adequate vascularization to provide oxygen and nutrients. Here we describe an approach for cell transplantation termed the Therapeutic Vascular Conduit (TVC), which uses an acellular vessel as a scaffold for a hydr...

Full description

Bibliographic Details
Main Authors: Edward X. Han, Hong Qian, Bo Jiang, Maria Figetakis, Natalia Kosyakova, George Tellides, Laura E. Niklason, William G. Chang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00150-2