Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells

Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells

NK cells are phenotypically and functionally diverse lymphocytes due to variegated expression of a large array of receptors. NK-cell activity is tightly regulated through integration of receptor-derived inhibitory and activating signals. Thus, the receptor profile of each NK cell ultimately determin...

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Bibliographic Details
Main Authors: Vera Schwane, Van Hung Huynh-Tran, Sarah Vollmers, Vivien Maria Yakup, Jürgen Sauter, Alexander H. Schmidt, Sven Peine, Marcus Altfeld, Laura Richert, Christian Körner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
NK cells
CD56bright
CD56dim
CD58
CD205
CD161
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.568927/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.568927/full

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