Activation of overexpressed glucagon‐like peptide‐1 receptor attenuates prostate cancer growth by inhibiting cell cycle progression

Activation of overexpressed glucagon‐like peptide‐1 receptor attenuates prostate cancer growth by inhibiting cell cycle progression

Abstract Aims/Introduction Incretin therapy is a common treatment for type 2 diabetes mellitus. We have previously reported an anti‐prostate cancer effect of glucagon‐like peptide‐1 receptor (GLP‐1R) agonist exendin‐4. The attenuation of cell proliferation in the prostate cancer cell line was depend...

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Bibliographic Details
Main Authors: Toru Shigeoka, Takashi Nomiyama, Takako Kawanami, Yuriko Hamaguchi, Tsuyoshi Horikawa, Tomoko Tanaka, Shinichiro Irie, Ryoko Motonaga, Nobuya Hamanoue, Makito Tanabe, Kazuki Nabeshima, Masatoshi Tanaka, Toshihiko Yanase, Daiji Kawanami
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of Diabetes Investigation
Subjects:
Cell cycle
Glucagon‐like peptide‐1 receptor
Prostate cancer
Online Access:https://doi.org/10.1111/jdi.13247

Internet

https://doi.org/10.1111/jdi.13247

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