FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

The Alzheimer disease (AD) amyloid protein precursor (APP) can bind the FE65 adaptor protein and this complex can regulate gene expression. We carried out yeast two-hybrid studies with a PTB domain of FE65, focusing on those genes that might be involved in nuclear signaling, and identified and valid...

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Bibliographic Details
Main Authors: Yuji Kajiwara, Afia Akram, Pavel Katsel, Vahram Haroutunian, James Schmeidler, Gary Beecham, Jonathan L Haines, Margaret A Pericak-Vance, Joseph D Buxbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19343227/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19343227/?tool=EBI

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