Combinatorial therapy with two pro-coagulants and one osmotic agent reduces the extent of the lesion in the acute phase of spinal cord injury in the rat

Combinatorial therapy with two pro-coagulants and one osmotic agent reduces the extent of the lesion in the acute phase of spinal cord injury in the rat

Abstract Background Spinal cord injury (SCI) is a complex disease that leads to a motor, sensitive, and vegetative impairment. So far, single therapies are ineffective for treating SCI in humans and a multifactorial therapeutic approach may be required. The aim of this work was to assess the effect...

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Bibliographic Details
Main Authors: Mathieu Boutonnet, Elisabeth Laemmel, Eric Vicaut, Jacques Duranteau, Marc Soubeyrand
Format: Article
Language:English
Published: SpringerOpen 2017-12-01
Series:Intensive Care Medicine Experimental
Subjects:
Spinal cord injuries
Combined modality therapy
Rats
Tranexamic acid
Fibrinogen
Saline solution hypertonic
Online Access:http://link.springer.com/article/10.1186/s40635-017-0164-z

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http://link.springer.com/article/10.1186/s40635-017-0164-z

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