Serotonin transporter genotype modulates resting state and predator stress-induced amygdala perfusion in mice in a sex-dependent manner.

The serotonin transporter (5-HTT) is a key molecule of serotoninergic neurotransmission and target of many anxiolytics and antidepressants. In humans, 5-HTT gene variants resulting in lower expression levels are associated with behavioral traits of anxiety. Furthermore, functional magnetic resonance...

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Bibliographic Details
Main Authors: Jann F Kolter, Markus F Hildenbrand, Sandy Popp, Stephan Nauroth, Julian Bankmann, Lisa Rother, Jonas Waider, Jürgen Deckert, Esther Asan, Peter M Jakob, Klaus-Peter Lesch, Angelika Schmitt-Böhrer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247311