Pharmaceutical Nanoparticles and the Mucin Biopolymer Barrier
Mucus in the gastrointestinal tract remains a tenacious barrier that restricts the passage of many orally administered compounds into the GIT’s epithelial layer and consequently into the systemic circulation. This results in significant decreases in the oral bioavailability of many therapeutic molec...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2012-12-01
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Series: | BioImpacts |
Subjects: | |
Online Access: | http://dx.doi.org/10.5681/bi.2012.029 |