Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice

Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice

Abstract Background Chronic prostatitis has been supposed to be associated with preneoplastic lesions and cancer development. The objective of this study was to examine how chronic inflammation results in a prostatic microenvironment and gene mutation in C57BL/6 mice. Methods Immune and bacterial pr...

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Bibliographic Details
Main Authors: Yong Gao, Lijuan Wei, Chenbang Wang, Yuanjie Huang, Weidong Li, Tianyu Li, Chaohua Mo, Huali Qin, Xiaoge Zhong, Yun Wang, Aihua Tan, Zengnan Mo, Yonghua Jiang, Yanling Hu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Biological Research
Subjects:
Chronic prostatitis
Prostatitis mouse model
Proliferative inflammatory atrophy
Prostatic intraepithelial neoplasia
Somatic genome mutation
Online Access:http://link.springer.com/article/10.1186/s40659-019-0237-4

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http://link.springer.com/article/10.1186/s40659-019-0237-4

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