BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

Protein Phosphatase 2A (PP2A) is a heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits. PP2A complexes with B56 subunits are targeted by Shugoshin and BUBR1 to protect centromeric cohesion and stabilise kinetochore–microtubule attachments in yeast and mouse meiosis....

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Bibliographic Details
Main Authors: Laura Bel Borja, Flavie Soubigou, Samuel J P Taylor, Conchita Fraguas Bringas, Jacqueline Budrewicz, Pablo Lara-Gonzalez, Christopher G Sorensen Turpin, Joshua N Bembenek, Dhanya K Cheerambathur, Federico Pelisch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
PP2A
meiosis
Bub1
B56
SLiM
Online Access:https://elifesciences.org/articles/65307

Internet

https://elifesciences.org/articles/65307

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