Discovery of potent, novel, non-toxic anti-malarial compounds via quantum modelling, virtual screening and <it>in vitro </it>experimental validation

<p>Abstract</p> <p>Background</p> <p>Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use today have high toxicity and low therapeutic indices. Gradient Biomodeling,...

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Bibliographic Details
Main Authors: Kaludov Nikola, Sullivan David J, Martinov Martin N
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/274