Dysbiotic oral microbiota and infected salivary glands in Sjögren's syndrome.

Key events in the pathogenesis of Sjӧgren syndrome (SS) include the change of salivary gland epithelial cells into antigen-presenting cell-like phenotypes and focal lymphocytic sialadenitis (FLS). However, what triggers these features in SS is unknown. Dysbiosis of the gut and oral microbiomes is a...

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Bibliographic Details
Main Authors: Jehan Alam, Ahreum Lee, Junho Lee, Dong Il Kwon, Hee Kyung Park, Jung-Hyun Park, Sumin Jeon, Keumjin Baek, Jennifer Lee, Sung-Hwan Park, Youngnim Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230667