Absolute Quantitation of DNA Methylation of 28 Candidate Genes in Prostate Cancer Using Pyrosequencing

Aberrant DNA methylation plays a pivotal role in carcinogenesis and its mapping is likely to provide biomarkers for improved diagnostic and risk assessment in prostate cancer (PCa). We quantified and compared absolute methylation levels among 28 candidate genes in 48 PCa and 29 benign prostate hyper...

Full description

Bibliographic Details
Main Authors: Nataڑa Vasiljeviš, Keqiang Wu, Adam R. Brentnall, Dae Cheol Kim, Mangesh A. Thorat, Sakunthala C. Kudahetti, Xueying Mao, Liyan Xue, Yongwei Yu, Greg L. Shaw, Luis Beltran, Yong-Jie Lu, Daniel M. Berney, Jack Cuzick, Attila T. Lorincz
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0790