Divergent organ-specific isogenic metastatic cell lines identified using multi-omics exhibit differential drug sensitivity.

<h4>Background</h4>Monitoring and treating metastatic progression remains a formidable task due, in part, to an inability to monitor specific differential molecular adaptations that allow the cancer to thrive within different tissue types. Hence, to develop optimal treatment strategies f...

Full description

Bibliographic Details
Main Authors: Paul T Winnard, Farhad Vesuna, Sankar Muthukumar, Venu Raman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242384