Rocuronium Has a Suppressive Effect on Platelet Function via the P2Y12 Receptor Pathway In Vitro That Is Not Reversed by Sugammadex

Rocuronium Has a Suppressive Effect on Platelet Function via the P2Y12 Receptor Pathway In Vitro That Is Not Reversed by Sugammadex

Rocuronium is an aminosteroid nondepolarizing neuromuscular blocker that is widely used for anesthesia and intensive care. In this study, we investigated the effect of rocuronium on human platelet functions in vitro. The effects of rocuronium on platelet aggregation, P-selectin expression, and cycli...

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Bibliographic Details
Main Authors: Yutaka Murata, Shuji Kawamoto, Kazuhiko Fukuda
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
rocuronium
sugammadex
morpholine
platelet
P2Y12 receptor
cyclodextrin
Online Access:https://www.mdpi.com/1422-0067/21/17/6399

Internet

https://www.mdpi.com/1422-0067/21/17/6399

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